Protein Modification Reagents
Cayman Chemical PAMAM Dendrimer G6 0 Amine w
An amine-terminated PAMAM dendrimer; has been used as a drug delivery system in vivo; ~67 Å in diameter and has 256 surface groups; active against clinical isolates of several bacteria (MICs = 0.25-25 UG/ml); increases the cell growth rate of HEK293T and HeLa cells from 100-500 nM but is cytotoxic to the same cells when used at ≥700 nM; increases the oral bioavailability of vardenafil in rabbits; has been used to deliver MRI contrast agents in mice
Medchemexpress LLC TCO-PEG2-amine | 2141981-87-3 | ≥97.0% | C15H28N2O4 | 25 MG
TCO-PEG2-amine is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are designed to degrade target proteins by connecting an E3 ubiquitin ligase ligand to a target protein ligand via a linker, leveraging the intracellular ubiquitin-proteasome system. This product appears as a colorless to light yellow liquid.
- PEG-based PROTAC linker
- Suitable for the synthesis of PROTACs
- Purity ≥97.0%
- Colorless to light yellow liquid appearance
- For research use only
Medchemexpress LLC T-Boc-N-amido-PEG5-tosylate | 1404111-69-8 | MFCD34596623 | 96.0% | 491.60 g/mol | C22H37NO9S | 1 G
A Boc-protected PEG5 tosyl linker for chemical conjugation and linker assembly. The reagent combines a hydrophilic five-unit polyethylene glycol spacer with a tosylate leaving group and a Boc-protected amine, providing improved solubility and enabling nucleophilic substitution for installation of PEG-based linkers in medicinal chemistry and bioconjugation workflows.
- Enhances aqueous solubility via PEG5 spacer.
- Enables nucleophilic substitution through tosylate leaving group.
- Protects primary amine with Boc for selective deprotection.
- Suitable for linker assembly and bioconjugation chemistry.
- Compatible with standard organic synthesis conditions.
New England Biolabs, Inc. Endo D – 1500 units
Endo D is a recombinant glycosidase, which cleaves within the chitobiose core of paucimannose N-linked glycans, with or without extensions in the antennae. Endo D is tagged with a chitin binding domain (CBD) for easy removal from a reaction, and is supplied glycerol-free for optimal performance in HPLC and MS- intensive methods.
Nanocs Ruthenium PEG Maleimide, 5 mg
Nanocs provides Ruthenium PEG derivatives for biomedical research use, 5000 Da.
Abcam Pyrido x atin, MMP-2 inhibitor, 250UG
MW 263.33 Da, Purity >95%. Free radical scavenger (IC₅₀ = 8 μM). MMP-2 inhibitor. Inhibits lipid peroxidation and DNA synthesis. Shows antifungal effects in vivo (IC₅₀ = 6 μM).
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Mal-N-bis(PEG4-C2-acid) | 2100306-52-1 | 98.0% | C29H48N2O15 | 50 MG
Mal-N-bis(PEG4-C2-acid) is a PROTAC linker utilized in laboratory chemical applications and the manufacture of substances. This high-purity compound features a molecular formula of C29H48N2O15 and a molecular weight of 664.70. It is suitable for various chemical synthesis projects, offering stability under recommended storage conditions for both pure and dissolved forms.
- High purity (98.0%)
- Functions as a PROTAC linker
- Suitable for laboratory chemical applications
- Stable for up to 3 years in pure form at -20°C
- Stable for up to 6 months in solvent at -80°C